Ross Noble Freewheeling will be a six-part series that puts the stand-up comic's fate entirely in the hands of the public.
Noble is famous for improvisation in his comedy routines and the show will follow a similar style with everyone able to suggest scenarios and take part.
The show has been described as "an anti-travelogue, a revealing comic journey and a fascinating insight into modern Britain".
"I can't promise this programme will be either insightful or that revealing but it's definitely a programme," joked Noble.
UKTV commissioner Richard Watsham said: "Ross Noble is the ultimate comic improviser but even so it's a brave thing to do to put yourself in the hands of the fans and take whatever is thrown at you.
"This format absolutely plays to his strengths however and I'm confident that the combination of innovation and humour with a really modern feel will appeal to a broad audience."
Exec producer James Woodroffe joked: "I'm slightly worried this could be my last job in TV."
Ross Noble Freewheeling will air on Dave in the autumn.