The singer will make her first UK TV performance in 12 years on the October 18 Sunday results show.
"I have always loved my UK fans and I'm thrilled to perform for them on The X Factor," she said. "I am also a fan of Simon Cowell's and look forward to meeting him. It should be a fun night."
Houston will release I Look To You, her first studio album since 2002, the day after her X Factor performance. The album debuted at number one on the US albums chart last month.
This week's X Factor results show will feature performances from Robbie Williams and Alexandra Burke. Shakira has also confirmed that she will perform on the ITV1 talent show this year.
> Click here to read our review of Whitney Houston's I Look To You album