The 18-year-old singer was axed from show yesterday amid rumours that he had bragged to production staff about taking cocaine.
Marvin Humes told BBC Newsbeat: "I think he's obviously let himself down and hopefully he's going to learn from this and bounce back in a positive way.
"It's disappointing because obviously he had a lot of fans and I'm sure he's going to regret it at some point, if he's not regretting it already."
Oritsé Williams added: "When you go on a show like that, you do become an example and in the public eye constantly. You can't hide anything - that's the thing about The X Factor.
"Hopefully, as Marvin said, he's going to learn from this and he'll bounce back positively. Everybody deserves a second chance."
> 'The X Factor's Golden Rules: What are they?
> Frankie Cocozza's 'X Factor' journey in pictures
> 'X Factor's Matt Cardle: 'Frankie Cocozza exit is fair enough'
Humes added that during JLS' time on the show in 2008, things were "really different", with strict 8pm curfews and bans on going out socially.
"What people have to remember as well is that this is one massive opportunity that truly can change your life," he said. "You can't treat it like it's a joke. For us it changed our lives and we treated it very seriously. You've just got to knuckle down and get on with the job."
Aston Merrygold said: "In regards to one minute no-one knowing your name to the next minute everyone knows your name and you're on the front of the paper and the whole country knows your name, there's no training for that.
"For the kids who are going in there who are 16, 17, it's obviously very, very hard for them... If you can't handle it it's an opportunity missed."
> 'X Factor' Frankie Cocozza 'thought drug use was no big deal'
> Kelly Rowland left speechless by 'X Factor' Frankie Cocozza axe: Video
> 'X Factor' Frankie Cocozza: Rock 'n' roll wally or wasted talent?
Watch Digital Spy's interview with Frankie and the X Factor Boys below:
See pictures of Frankie Cocozza on The X Factor below: