The former X Factor contestant defended the flamboyant singer, stating that she would have saved him from elimination last weekend if she were a judge.
Kye Sones was sent home by judges Tulisa Contostavlos and Nicole Scherzinger, with Clark remaining in the competition.
"It's not just a singing competition. It's an entertainment show," Misha B told Yahoo.
"I watched the sing off with Kye and Rylan. From that performance, I would've saved Rylan too because it was an amazing performance."
She added: "When you look at all the hype around Rylan, he keeps everyone guessing and it's exciting."
Robbie Williams recently stated that Clark should duet with Kylie Minogue if he reaches the X Factor final.
Misha B is set to reach the UK singles chart top ten with her new single 'Do You Think Of Me'.
The X Factor continues on Saturday (November 10) at 8pm on ITV1.
Watch Rylan Clark perform in the X Factor sing-of below: