The Scottish singer, who recently appeared on The Oprah Winfrey Show, has been given odds of 4/6 by William Hill to be crowned this year's champion.
Staffordshire teenager Shaun Smith, who won a standing ovation for his version of Bill Withers's 'Ain't No Sunshine', is currently in second place with odds of 11/2.
Pizza delivery man Jamie Pugh has been given a 6/1 chance, while ten-year-old Hollie Steel is sitting on a 9/1 possibility of triumphing. Student Sue Son, who was told to ditch her partner by the judges, has been given odds of 25/1.
Boyle shot to international stardom after wowing audiences with her performance of 'I Dream A Dream' from Les Miserables, while a YouTube clip of her appearance has been viewed more than 100 million times.
Britain's Got Talent continues this Saturday on ITV1.
> Click here to see the latest odds from William Hill