The Life Stories host, who has appeared on the talent show's judging panel since its debut in 2007, told the Daily Mail that his forthcoming role as replacement for veteran CNN anchor Larry King will make it impossible to film the next series of Britain's Got Talent.
Morgan said: "There's been considerable speculation about what my new CNN job means for my role on Britain's Got Talent.
"Well, sadly, I can now confirm that I will have to quit BGT, as I will be ensconced in New York interviewing popes, presidents, pugilists and popstars when the auditions are filmed next year."
He added: "I'll miss the late-night drinking sessions with Amanda [Holden], and Ant and Dec - for Geordie midgets, they can pack it away... Most of all, I'll miss winding up my co-judges, and being wound up by them.
"Amanda, please stop crying; I'll still find time to see you in my American trailer. And Simon, thanks - sincerely - for the ride. It's been a blast."
> Holden calls for Robinson Britain's Got Talent role