New Look and other major fashion chains have been approached by the makers of the ITV2 show with the idea of stocking clothes inspired by its stars.
Lime Pictures may follow up the deal by launching a TOWIE beauty range.
New Look has previously teamed up with Giles Deacon and Lily Allen for fashion ranges. Amy Childs, Sam Faiers, Lauren Goodger and Lauren Pope may be the next celebrities to work with the brand.
Sam Faiers told Digital Spy earlier this year that she had ambitions to start a fashion career.
The Only Way Is Essex returns for a third series in the autumn.
> 'TOWIE' Mark Wright has James Bond ambitions
> 'The Only Way Is Essex' Amy Childs poses naked in photoshoot