The E4 cult comedy-drama's renewal was officially announced at a press event this morning (March 19).
The fourth series of Misfits - which introduced a new regular cast - aired on E4 in late 2012.
Series star Matt Stokoe (Alex) told Digital Spy in December that a fifth run had been "planned" but that the show's cast were still waiting for an official confirmation.
"I think they'd like to do it," the actor said at the time. "It's all up in the air and we won't find out until quite late if it's going again. I think it's planned, but nothing's set in stone yet."
Misfits creator Howard Overman previously revealed that he is working a movie version that could potentially bring back old characters.
"If it happens, it will involve past and present characters," he revealed in November. "Whether or not you've completely seen the end of Simon (Iwan Rheon) and Alisha (Antonia Thomas) if our movie has its way, is another issue."
Overman is also working with BBC One on new fantasy drama Atlantis, which is being eyed as a replacement for the popular series Merlin.
> Misfits review: Four Horsemen, sex and love in series four finale
Watch a clip from the last series of Misfits below: (Warning: Contains strong language and adult humour)