The pair will battle it out until Friday, when whoever fails to win the public vote will be evicted from the compound.
Karly was one of the housemates to nominate Freddie, reasoning: "I find him overbearing, he makes me cringe." Lisa said of the Oxford graduate: "He just aggravates me a bit sometimes."
Sree voted for Sophia, describing her as "really argumentative", while Noirin said that she was "aggressive".
"She's slagging people and being non pro-active with things in the house," she added.
Sree was the pair's closest rival, receiving four nominations, while Rodrigo, Kris and Angel were the only housemates to receive no nominations.