The foursome have the shortest odds on leaving the show this evening, when eight housemates face the public vote.
John James is rated at 1/5 by Paddy Power and is the hot favourite for the chop, while Sam (6/1), Steve (7/1) and Dave (10/1) are also believed to be in trouble.
Punters can back Corin to be one of the contestants leaving at 14/1, while Mario is currently 16/1. Andrew and boxer JJ are thought to be safe with relatively long odds of 20/1 and 40/1 respectively.
Josie remains the favourite to win Big Brother 11 with current odds of 1/2.
Big Brother airs tonight at 9pm on Channel 4.