Speaking to Emma Willis on last night's Bit on the Side, the former EastEnders actress admitted that she "hates" the Shannon twins, and described them as "poison".
She said: "I believe when Nicola watches back she will see what [the twins] pulled her into, and I feel they pulled her into going tonight."
The star went on: "I want the twins out, but if the twins didn't stay, the show wouldn't be as fun. They're good telly, but I hate them."
Kirk Norcross, also a guest on the Channel 5 spinoff show, backed up her claims by saying: "The twins dragged her into something - they are vile."
Defending McLean's integrity, Cassidy added: "I experienced 16 days with the girl and [Nicola's] amazing, so it's very hard to stomach. But I saw the change - when you're in the house, you have to spend time with [everyone] - unfortunately the twins are poison."
> Celeb Big Brother's Nicola McLean: 'Denise Welch clash cost me'
Watch Nicola McLean's eviction from Celebrity Big Brother below: