The glamour model said she wouldn't "feel very comfortable" living with a bunch of strangers in the famous house, which has previously been inhabited by her ex-boyfriend Kirk Norcross and former TOWIE star Amy Childs.
Speaking to Digital Spy, Pope commented of Celebrity Big Brother: "I think it would just creep me out when you're on the toilet knowing that someone can see you.
"I think I'd get nervous and never go to the toilet and just get really poorly.
"I like to be comfortable around the people I'm with. I don't think I'd feel very comfortable being in a situation like [the Big Brother house]."
Asked how she thought Norcross came across when he appeared on Celebrity Big Brother earlier this year, Pope simply stated: "Not very well."
[Kirk Norcross is evicted from the Celebrity Big Brother house]
She also told DS that she "didn't have a clue" Norcross would be returning for the latest series of TOWIE until she saw him on TV.
Katie Price and controversial X Factor contestant Rylan Clark have reportedly been approached for the next edition of Celebrity Big Brother, which airs on Channel 5 in January.
The show unveiled its new eye logo earlier this week in a wintery promo picture starring hosts Brian Dowling and Emma Willis.
Pope was speaking to promote the Motorola Razr i.