Heidi and Spencer were immune from the face-to-face nominations after being sent to the Big Brother basement in a secret twist.
The remaining housemates were asked to pick the people that they wanted to nominate from a pack of cards with the contestants' faces on.
They had to pick two cards and then voice their reasons in front of their co-stars.
Ryan and Sam ended up picking up the most votes and will go head-to-head to avoid becoming the second housemate evicted.
Supermodel Paula Hamilton became the first celebrity to be voted off the show last night (January 9).
Celebrity Big Brother airs every night on Channel 5.