Matronic, who is a guest on this week's Voice UK Battle Rounds, said that she felt more comfortable working on the BBC series than on one of Cowell's shows, arguing that the Syco boss was "not very constructive".
"He is someone who has always been in a position of power and you can see that. You can smell the power coming off that guy," Matronic told The Sun.
"There is a sensitivity chip missing. I am not one of those women who find success an aphrodisiac. There are a lot of people who find success and power the ultimate aphrodisiac, but it is not for me."
She added: "He might be a perfectly lovely person and if he likes comic books and weird funny movies then we would probably get along but I somehow doubt that."
Matronic is the Battle Advisor helping out coach Jessie J this weekend. Other Battle Advisors on the show include Paloma Faith and former Catatonia singer Cerys Matthews.
The Voice UK's Battle Rounds airs on Saturday and Sunday (April 21 and 22) at 7pm on BBC One.
Scissor Sisters will perform on The Voice UK live shows on May 12, previewing their new single 'Only The Horses'.
> Emeli Sande confirmed for 'The Voice' UK live show performance
> 'The Voice' UK: Digital Spy picks The Ones to Watch
Watch a behind-the-scenes look at Scissor Sisters' new video below: