The duo currently have the shortest odds for the chop in this week's six-way double eviction vote. Paddy Power rates Makosi as the 11/10 favourite for the axe, while Nadia is close behind at 5/4.
Former Celebrity Big Brother winner Ulrika can be backed at 8/1, while Nikki is currently rated at 12/1.
'Nasty' Nick Bateman has odds of 14/1 to depart, while Chantelle is considered safe with long odds of 50/1 that she will be leaving.
The latest Big Brother eviction show airs live on Friday at 9pm on Channel 4.