The reality show will follow the lives of globetrotting 20-somethings in South West London, who are among the world's most elite socialites. The project has been compared to hit US MTV series The Hills.
The broadcaster has promised to expose the "real life relationships" behind the "posh accents, fast cars and glamorous holidays" of the Chelsea social circuit.
Among the cast are polo player Francis Boulle, who has been romantically linked to Emma Watson, pop hopeful Caggie Dunlop, "mischievous" party goer Millie Mackintosh, Harrovian Hugo Taylor and Etonian Spencer Matthews.
Also taking part in the project are fashion student Amber Atherton, gossip girl Rosie Fortescue, model and pianist Fredrik Ferrier, socialite Alexandra Felstead, blogger Francesca Hull, party host Ollie Locke and Greek musician Gabriella Ellis.
Made In Chelsea launches on Monday, May 9 at 10.15pm on E4.
> E4 orders Chelsea Girls series