Made in Manchester has been rumoured to be in pre-production by Monkey Kingdom, as a new series similar to its previous show set in London.
Coronation Street's Brooke Vincent, Waterloo Road's Chelsee Healey and Manchester designer Nadine Merabi were among the stars linked to the alleged show.
However, Monkey Kingdom has told Manchester Confidential that the rumours are false.
When asked if it is producing a new series in the area, it stated: "We are not."
Merabi added: "It's not true. There is something being discussed at the moment but it's not Made In Manchester and nothing has been finalised or agreed yet.
"Chelsee read the rumours in the paper just like everyone else and rang me to ask me what it was all about. She did say she would love to do it though if it were real."
Vincent and Healey's casting representatives Laine Management also said that it had not heard of such a programme.