The Coronation Street actress said that she is ideal for the show as she worked in a Selfridges store and knows about the company's history.
"I would absolutely love a part in Mr Selfridge," she told The Sun. "I'm qualified after all, and I know the history behind it all.
"When I first started working in Selfridges, we had a big talk about when and how it first opened and they talked about founder Mr Selfridge as well."
Keegan worked at a make-up counter at a Selfridges in Manchester prior to landing the role of Corrie's Tina McIntyre.
Meanwhile, the 25-year-old has also hinted that she is contemplating the idea of launching a fashion line, telling What's on TV: "I've always been interested in fashion, always.
"I love shopping and I love putting outfits together and accessories and things like that, so I'd love to do my own fashion thing... I don't know... maybe in the future... watch this space."
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