First words: "What are you doing here?"
A battle against the Cybermen in the South Pole took its toll on the increasingly frail Time Lord, who lapsed in and out of consciousness while trying to fend off the Mondasian threat. He was taken captive by the Cybermen and held inside their spaceship, but had enough presence of mind to allow the invaders to drain too much power from the Earth and destroy their home planet.
In front of companions Ben and Polly, the grouchy white-haired time traveller collapsed inside the Tardis and transformed from the ailing William Hartnell into the endearing cosmic hobo Patrick Troughton.
Last words: "'It's all over'. That's what you said. No, but it isn't. It's far from being all over. I must get back to the Tardis immediately! I must go now… I must go at once. [Ben passes a cloak to The Doctor] Ah yes, thank you. Keep warm."
First words: "Araagh, slower! Concentrate on one thing! One thing!"
Recent adventures have displayed The Doctor's fondness for his Time Lord race, but they didn't do his second incarnation many favours. In fact, they found him guilty of interfering in the affairs on other planets and exiled him on Earth - along with forcing a regeneration upon him. The last moments of Patrick Troughton were as a disembodied head floating away in a dark void. The next time we saw The Doctor - in glorious colour - was when Jon Pertwee stumbled out of the Tardis and collapsed.
Last words: "Is this some sort of joke? No, I refuse to be treated in... What are you doing? No! Stop! You're making me giddy! No! You can't do this to me. No! No! No! No! No! No! No!"
First words: "Shoes, must find my shoes. Unhand me, Madam!"
Big spiders send shivers down the spines of many folks, but rarely do they make anyone regenerate. The Doctor's indirect destruction of angry arachnid 'The Great One' on Metebelis 3 caused a huge wave of radiation to fill its cave after it was tricked into using a crystal for its evil purposes. This radiation weakened The Doctor and affected his cells, although he made it back to UNIT headquarters. He regenerated in front of the Brigadier, Sarah Jane and Harry Sullivan, before quickly bounding around with a radically eccentric personality and jelly baby fetish.
Last words: "A tear, Sarah Jane? No, don't cry. While there's life, there's..."
First words: "Stop Linx... the course of human history... I tell you, Brigadier - there's nothing to worry about. The Brontosaurus is large and placid."
Video killed the radio star, but it was a radio telescope that curtailed the Fourth Doctor's reign. A bid to unplug a power cable and prevent The Master from sending out a universal message from the telescope caused The Doctor's mortal foe to tilt the big satellite dish and leave him dangling high above the ground. Intensely staring straight ahead, The Doctor kept hanging on while experiencing visions of old enemies like the Daleks urging him to die. Then, suddenly, he lost his grip and fell to the ground.
Out of nowhere, the mysterious figure of The Watcher moved over to The Doctor, merged bodies with him and transformed into the younger Peter Davison. Bafflingly, it transpired that The Watcher was the future Doctor all along.
Last words: "It's the end, but the moment has been prepared for."
First words: "Ah, you've come to help me find the Zero Room. Welcome aboard. I'm The Doctor, or will be if this regeneration works out."
Everything seemed to be going well for this youthful and sprightly incarnation until he paid a major price by saving the life of his dying companion Peri. They were both suffering from spectrox toxaemia, and the only cure was bat's milk located in an oxygen-free cave deep down in the planet Androzani. It's certainly not something you can pick up at your local Tesco. Sadly, there was only enough milk for Peri and she could only look on as her friend collapsed on the Tardis floor.
In a memorably tense scene, The Doctor experienced hallucinations featuring a range of former friends and foes, who either implored him to survive or die. The Master was particularly vocal in his desire for The Doctor to push up the daisies, but suddenly our hero's head jolted up from the Tardis floor - complete with blond afro and an inconspicuous blink.
Last words: "Going soon. It's time to say goodbye. Might regenerate, I don't know. Feels different this time. Adric?"
First words: "You were expecting someone else?"
After Colin Baker was harshly sacked from the role and refused to return for a regeneration scene, Sylvester McCoy had to wear a curly blond wig and be filmed from behind wearing the multicoloured Sixth Doctor outfit. Not exactly the most dignified start to a new era on the show, but at least his previous incarnation's final words were a rant against his companion Mel's fondness for vegetable juice.
An attack on the Tardis by a Time Lady called The Rani forced the vessel to crash land and The Doctor to regenerate from the resulting injuries.
Last words: "Carrot juice, carrot juice, carrot juice."
First words: "That was a nice nap. Now, down to business."
It wasn't any monsters from outer space that did it for The Doc - it was his beloved human race! He emerged from the Tardis in San Francisco and was immediately pelted with a volley of bullets from some angry Triads. Welcome back to Earth. To make matters worse, The Master was on the loose and Dr Grace Holloway ignored the Time Lord's protests and tried to operate on him despite his distinctly non-human internal organs. Two hearts beating together certainly weren't in Grace's medical textbooks.
Her efforts failed and the seemingly deceased man was locked away in a morgue, only to regenerate into a floppy haired and housewife-pleasing younger persona with a Jesus Christ complex and dubious fashion taste.
Last words: "Got to stop him."
First words: "Who am I? WHO AM I?"
The exact circumstances regarding his regeneration are unknown, although it is strongly believed that he perished during the epic Time War. Evidence suggests that the Eighth Doctor regenerated shortly before his successor encountered the Autons and a certain chavette companion called Rose, as he notably comments on his new features when looking in the mirror at Jackie Tyler's flat. Yes - we know that Christopher Eccleston was the Ninth Doctor not the Eighth, but that photo on the left is as close to the regeneration as we can visually get!
Last words: "Right, where to next? Now, where was I? [Record starts skipping in the Tardis] Oh no, not again!"
First words: "Run!"
A short-lived and undoubtedly 'fantastic' stint was brought to an end after The Doctor sacrificed himself, just like his fifth incarnation, to save his companion. Cellular degeneration and regeneration into Barcelona-bound David Tennant ensued once he sucked out and absorbed the Time Vortex from Rose Tyler's mouth. Has anyone else ever found a better pretext for a sloppy snog?
Last words: "Rose, before I go I just want to tell you you were fantastic. Absolutely fantastic. Do you know what? So was I."
First words: "Hello. OK, mmm. New teeth. That's weird. So where was I? That's right. Barcelona."
The four knocks of the seemingly harmless old soldier Wilfred Mott signalled the end for the Tenth Doctor, as he sacrificed himself to save his companion by absorbing loads of nuclear energy. Hang on, is anyone getting a slight bit of déjà-vu here? Still, at least he didn't actually snog Wilf, instead trading places with him in a glass chamber.
After reaping his ‘reward’ and helping some old friends, The Doctor's body finally gave up the fight and the Ood mourned his passing with a bit of a sing-song (sadly not 'For He's A Jolly Good Fellow'). The change into Matt Smith occurred once The Doctor clambered back inside his Tardis after visiting Rose back in 2005.
Last words: "I don't want to go!"
First words: "Aaargh! Legs! I've still got legs. Good. Arms, hands, ooh fingers, lots of fingers. Ears, eyes, nose, I've had worse. Chin, blimey. Hair! I'm a girl! No! No, I'm not a girl… and still not ginger! There's something important, I'm… I'm… crashing! Haha! Woohoo! Geronimooooo!"
We'll have to wait until spring to see what delights the new era of Doctor Who has in store for us. But as with every regeneration, the end is just the beginning…