He told Collider that the US-based opening two-parter would feature scenes "set in New York and San Francisco".
"It is Doctor Who's love letter to the States," said Wenger. "Last year started with the Tardis crash-landing on Big Ben in London and that was an opportunity for British audiences to be reminded of [the show's] British heritage. But this year, it's all about America."
He continued: "It's all about taking the show out to the States and seeing what Doctor Who will feel like set in America and in some very iconographic parts of the...landscape."
Wenger also confirmed that upcoming Christmas special, 'A Christmas Carol', "kind of riffs on the Dickens story [of the same name]".
"There's no one called Scrooge in it and it's not set on Earth, but there are familiar archetypes from that story within it that will please fans of Dickens's original," he said.
'A Christmas Carol' will air in December on BBC One. The sixth series of Doctor Who will follow in early 2011.