Warwick Davis (Life's Too Short), Jason Watkins (Being Human) and Tamzin Outhwaite (EastEnders) will all appear in the 2013 adventure.
The instalment will see the Doctor (Matt Smith) and his new companion (Jenna-Louise Coleman) encounter the Cybermen and a band of misfits - played by Davis, Watkins and Outhwaite - on a mysterious planet.
Doctor Who's lead writer and exec producer Steven Moffat said: "Cybermen were always the monsters that scared me the most! Not just because they were an awesome military force, but because sometimes they could be sleek and silver and right behind you without you even knowing."
He added: "And with one of the all-time classic monsters returning, and a script from one of our finest novelists, it's no surprise we have attracted such stellar names as Tamzin, Jason and Warwick."
The Cybermen - created by Kit Pedler and Gerry Davis - first appeared on Doctor Who in 1966 and last featured on the sci-fi drama in 2011 episode 'Closing Time'.
Doctor Who will return to BBC One this Christmas for a festive special, with eight episodes to follow in spring 2013.
> Neil Gaiman confirms new Doctor Who episode for 2013
> Matt Smith: 'Neil Gaiman Doctor Who episode will be a fan favourite'
Watch a teaser trailer for the Doctor Who Christmas special below: