An article from the Birmingham Mail claims that current Who star Matt Smith will be joined by his seven surviving predecessors.
Tom Baker, Peter Davison, Colin Baker, Sylvester McCoy, Paul McGann, Christopher Eccleston and David Tennant are all said to be appearing in the November one-off.
In addition, the report claims that the Steven Moffat-penned episode will use "studio trickery" to include appearances from the first three Doctors - played by the late William Hartnell, Patrick Troughton and Jon Pertwee.
The BBC is yet to confirm any official plans for the Doctor Who special, which will mark 50 years since the sci-fi drama's first transmission on November 23, 1963.
Showrunner Moffat recently confirmed that he has "immense", "considerable" plans for the anniversary but refused to reveal specifics.
Doctor Who will return to BBC One with new episodes later this year.
> Doctor Who anniversary biopic hires 'Misfits' producer Matt Strevens
> Tom Baker, Peter Davison, Paul McGann for Doctor Who audio special
Watch a trailer for Doctor Who's 2013 run below: