Rumours emerged last night that the Luther actor will appear in Peter Capaldi's first full series of the sci-fi drama.
However, a BBC spokesperson told Digital Spy that reports linking Smiley to the show are "just speculation".
Smiley's agent also refused to comment on the rumours after being contacted by DS.
The actor and comic has previously collaborated with filmmaker Ben Wheatley - currently shooting Doctor Who in Cardiff - on the films Kill List (2011) and A Field in England (2013).
His previous TV credits include episodes of Spaced, Utopia and Black Mirror.
Doctor Who series eight will air on BBC One in late 2014.
Doctor Who series 8: Peter Capaldi age makes no difference, says Moffat