Nominated for the gong are ITV2's divisive comedy panel series Celebrity Juice, BBC drama big hitter Sherlock, quaint cookery contest The Great British Bake Off, Channel 4 uni comedy Fresh Meat, Sir David Attenborough's Frozen Planet, and acclaimed documentary series Educating Essex.
Tube Talk's writers have picked out our favourite shows from the list below, but do you agree with our picks?
Sherlock (Selected by TV reporter Morgan Jeffery)
If we're talking an 'Audience Award', then surely Sherlock is the rightful winner? No other drama series - not even Steven Moffat's other baby Doctor Who - so completely captured the public's imagination in early 2012. It's an even more remarkable achievement when you consider that the Benedict Cumberbatch detective drama only aired for three weeks.
Sherlock manages the rare feat of being both fiendishly complex and broadly populist - over 10m viewers can't be wrong. And given Martin Freeman's face when TOWIE triumphed last year, we think he'd appreciate the win too.
Watch a Sherlock trailer:
Celebrity Juice (Selected by Entertainment reporter Daniel Sperling)
Celebrity Juice may be this year's TOWIE equivalent and there will undoubtedly be a similar outpouring of outrage from the telly snobs if it wins. What those people already scoffing at its
inclusion forget though is that Keith Lemon's lewd, surreal and tacky panel show has achieved phenomenal ratings and become one of the most influential programmes of the last few years. And no, I'm not joking about that last part.
Phrases like "bang tidy", "smash your back doors in" and "potato" have entered the public consciousness, and I don't think anyone's referred to Holly Willabooby by her real name since 2008. It's technically trash, but it's also harmless and uplifting and should be rewarded for all it's achieved. Also, who among you can say you're not curious as to what Keith will come out with up on that stage?
Watch a Celebrity Juice trailer:
Fresh Meat (Selected by TV Editor Alex Fletcher)
We often look to the US for great new TV comedy, but Fresh Meat proved that the British can still do it as well as anyone. After creating Peep Show, Sam Bain and Jesse Armstrong had a lot to live up to, but their take on modern student life was smart, occasionally surreal, but most importantly funny.
With breakout turns from rising stars Zawe Ashton and Greg McHugh and a stunning comic performance from Jack Whitehall, the show deserves recognition for attempting to break the mould when so many sitcoms are resorting to old-fashioned formats and easy quick-fire gags. Series two can't come quick enough.
Watch a Fresh Meat trailer:
What show do you think should win the YouTube Award? Do you agree with our writers? Or do you think something else should win? Share your verdict below!