Jonathan LaPaglia ("Seven Days" ) joins the cast as Kevin Debreno, the newest member of Mannion's team. Emmy award-winner Jean Smart ("Frasier"), who is currently nominated for an Emmy Award for this role, returns as Mannion's ex-wife, Sherry Regan. Joanna Cassidy ("Six Feet Under") guest stars as restaurateur Teddy Reed.
A high-profile missing persons case results when a young Caucasian woman who worked for a United States Congressman disappears. At the same time, a poor African-American woman with a drug habit is also missing and the black community is in an uproar when it is widely believed that the police are spending more time trying to find the rich white woman. Mannion, however, refusing to bow to political pressure, takes a stand and is determined to find both women before it's too late. In addition, the team still suffers from the loss of Detective McGregor, while his replacement and Temple's new partner, Kevin Debreno (LaPaglia), rubs a few of them the wrong way.
Meanwhile, Ella returns to work after three months of chemotherapy with mixed reactions from her co-workers.