The show, recently granted a season order by NBC, will drop three of its cast regulars - Sydney Tamiia Poitier, Yancey Arias and Bruce Davison - and draw more parallels with its '80s predecessor.
Showrunner Gary Scott Thompson told The Hollywood Reporter: "It's a reboot. We're moving away from the terrorist-of-the-week formula and closer to the original, making it a show about a man and his car going out and helping more regular people, everymen."
The rejigged Knight Rider will debut as a two-parter in January, with the first part slated to air after a Sunday night NFL match and the second on the following Wednesday.
The show will not add any new cast regulars, instead focusing on the characters of Mike (Justin Bruening), Sarah (Deanna Russo), Billy (Paul Campbell), Zoe (Smith Cho) and KITT.