The 48-year-old actress was recently confirmed to reprise her Amanda Woodward role on The CW reboot, beginning on the Tuesday, November 17 episode.
Locklear told Extra that it would be "great fun" for her character to be reunited with Dr Peter Burns, who Wagner portrayed from 1994 to 1999.
The pair, who have been dating in real life since 2007, were last seen on the final episode of the first incarnation of the Fox series as newlyweds who had faked their own deaths and moved to a remote island.
She said: "[He's] my favourite person to hang out with besides my daughter [Ava]. So, yeah, I want him all the time."
Locklear added that if he was to return to his former television residence, sharing romantic scenes with another actress would be "a no-no", saying: "[He could only have love scenes] with me, kissing me, everything me."