The programme's executive producer Bill Lawrence recently confirmed that he is considering a different title for the series as the premise has changed since the pilot.
Cox, who stars in the show as Jules, has now claimed that the current name could be misleading.
"We've been talking about [a name change] for a long time," she told Access Hollywood. "I don't know if it's going to happen or not. I don't know... I honestly don't know."
She continued: "This show is not just for women. It's for women and men. It's funny. It's crazy. It's kooky and you know it's heartfelt and it's all of that. So... we don't want people to get misled by the name Cougar Town. It's just about trying to get what the real show is about and we may do it or we may not."
Cox's co-star Busy Philipps recently admitted that she has "mixed emotions" about a possible name change.