The AP reports that the actor will be honoured with the Bob Hope Humanitarian Award at the ceremony for his work on the 'Hope For Haiti' television special.
Clooney's fundraising for victims of Hurricane Katrina and his efforts to raise awareness about the genocide in Darfur also contributed to his nomination.
The Academy of Television Arts and Sciences' chairman John Shaffner claimed that Clooney was the "obvious choice" to receive the award because of the way he uses television to encourage people to help.
Clooney is the fourth person to receive the award after Oprah Winfrey, Bill Cosby and Danny Thomas. He will accept the honour at the Primetime Emmys on August 29.