Speaking to Entertainment Weekly, series creator Bill Lawrence confirmed that Aniston will appear on the show's upcoming second season premiere with star and ex-Friends castmate Courteney Cox.
"She's going to play Courteney's shrink named Bonnie," he said.
Lawrence added: "[She's] kind of a get-too-involved-in-her-life type of therapist. Those guys are so close in real life they kind of do that for each other anyway. Bonnie has the life Jules wishes she has."
The former co-stars were last seen on screen together in Cox's FX series Dirt.
Lawrence added that the two are enjoying working with each other on the show.
"It starts and ends with Courteney and Jennifer being really great friends and excited to work together again - especially doing comedy together," he said.
"Every day that those two talk they have more ideas about [the role]. It's definitely something they're both involved in creatively."
Cougar Town premieres September 22 on ABC.