Entertainment Weekly reports that the actor will appear in multiple episodes as Deputy Chief Ted Carver.
Described as "savvy" and "hard-nosed", Carver will clash with Mac Taylor (Gary Sinise) when a sniper begins targeting New York citizens.
Larroquette previously played Carl Sack on Boston Legal and has also appeared in episodes of House and Chuck.
CSI: NY will return to CBS on September 24. Larroquette will make his first appearance on November 5.