The drama, which stars Leslie Bibb, focuses on a recently divorced single mother who returns to the neighbourhood where she grew up. The project is based on Kim Gatlin's book of the same name.
In a press release on its website, the PTC asked its members to sign a petition protesting against the title of the pilot.
The group's president Tim Winter said: "ABC's decision is not only an affront to women, it blatantly attacks the world's largest faith. The 'B-word' is toxic and is used to degrade, abuse, harass, bully and humiliate women. And the 'Christian' element only adds insult to injury. Regardless of whether the title ultimately makes it to broadcast, ABC has publicly proclaimed its values and it has tarnished the Disney brand [which owns the network].
"Would ABC even consider another faith to denigrate? Would they even consider a programme title or plot line based on 'Bitches' who were Muslim, Hindu, Jewish or Buddhist? I suspect not, and I certainly hope not. So why the double standard?"
Winter also complained about another of ABC's pilots, Don't Trust The Bitch In Apartment 23, and criticised "what appears to be a concerted effort to popularise profanity on network television".
He added: "Unless or until ABC realises that its decision about Good Christian Bitches was misguided, PTC will use every method at its disposal to turn advertisers and viewers away from a provocative title that compromises respect for both women and Christians in an attempt to draw ratings."
Last season, the PTC unsuccessfully campaigned for the title of CBS's sitcom $#*! My Dad Says to be changed.