The comedy, which comes from Rescue Me creator Peter Tolan, focuses on a group of people working at a theme park called Pilgrim Village.
TV Line reports that Blackburn has now signed up to play John Lichtfield, one of the park's employees.
Blackburn's role in Brave New World is not expected to interfere with his current part as Caleb in Pretty Little Liars as the shows are filmed at different times.
Pretty Little Liars' executive producer Olive Goldstick explained: "We will indeed see our Caleb again... [Tyler] will be available to us until July, so we're not that concerned."
Brave New World will also star Ed Begley Jr, Nick Braun, Will Greenberg, Jazz Raycole, Robbie Benson and Anna Popplewell.