The TBS sitcom will cease production later this year and will be replaced by the showbiz mogul's new series For Better or Worse, based on his Why Did I Get Married? films, reveals The Hollywood Reporter.
"Even though it will be sad to say goodbye to House of Payne, I'm really looking forward to exploring new territory with For Better or Worse," Perry explained.
"Working on House of Payne taught me a lot about what it takes to make a successful television series and I'm looking forward to applying that experience to For Better or Worse."
For Better or Worse will star Michael Jai White and Tasha Smith. It will unveil ten episodes, with the opportunity for an additional 90 pending satisfactory ratings returns.
TBC executive vice president Michael Wright said: "Tyler Perry's series have been tremendously successful for TBS, helping establish the network as a prime destination for African-American viewers.
"Given such a remarkable track record, we're excited for the opportunity to expand our relationship with Tyler Perry and Debmar-Mercury with the new series For Better or Worse."
> Tyler Perry: 'Spike Lee can go to hell'
Tyler Perry will "stay above" Spike Lee slams