The project starred Minnie Driver as Mary Beth, a single mother who teams with a streetwise conman (Brandon T. Jackson) to solve crimes.
Deadline reports that Hail Mary had emerged as an early favourite at the network, but was eventually passed over.
However, the pilot is still said to have the support of producing studio Warner Bros. Television and is currently being offered to other networks.
CBS recently picked up three pilots - The 2-2, Unforgettable and How to Be a Gentleman - to series, but also axed sophomore shows $#*! My Dad Says, Mad Love and The Defenders.
The network's official fall schedule is expected to be confirmed soon at the 2011 upfronts.
> Keep up to date with all the latest news on the 2011/12 television season