The Australian comedienne, who stars in the comedy Bridesmaids, appeared on Conan O'Brien's chatshow and proceeded to dish the dirt on former fellow cast members Nicolas Cage and Olivia Newton-John.
According to The Daily Telegraph, Wilson said that was strictly instructed not to talk to or look at Cage while filming Ghost Rider.
She also claimed that she discovered the actor was wearing a wig when she grabbed at his hair.
Wilson added that Newton-John made her power-walk to the set of A Few Best Men in Australia in January and "pushed" her to eat special "digestive enzymes from the Amazon" each day. "She's like a dealer of them," she added.
She also described her co-star as "so hilarious".
After the star disclosed her Hollywood secrets, O'Brien exclaimed: "This is an amazing interview, I never get dirt like this in an interview. This is amazing!"
Bridesmaids is out now in the US and opens on June 22 in the UK.
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Watch Rebel Wilson's interview with Conan O'Brien below: