The show, which will air on FX in the US, focuses on Wood's character Ryan. Ryan begins to see his neighbour's dog Wilfred (Jason Gann) as a man in a dog costume.
BBC Three controller Zai Bennett has now announced that he has picked up the comedy, which is based on an Australian series.
Chris Klein, Rashida Jones, Nestor Carbonell, Mary Steenburgen, Jane Kaczmarek and Ed Helms have also signed up to appear in the show.
Wood has previously described Wilfred as "bizarre", while executive producer David Zuckerman has suggested that it resembles the movie Fight Club.
Wilfred is scheduled to premiere on June 23 in the US, and is expected to be broadcast in the UK this autumn.
Watch a trailer for Wilfred below: