The project focuses on Paul (Steven Pasquale), a day trader who is fired from his job after a mistake costs his firm millions, according to Deadline.
Moving to Brooklyn, Paul encounters Marino (Anthony Carrigan) and the pair start up a high-end betting business.
Off The Map star Dhavernas will play Paul's wife, a professional photographer who specialises in nude portraits, according to Deadline.
The actress previously played the lead role of Jaye Tyler on Fox's Wonderfalls and has also appeared in episodes of The Pacific and Law & Order: Criminal Intent.
Her film credits include 2006's Hollywoodland, 2010's The Switch and forthcoming sci-fi film Mars et Avril.
Hung director Bronwen Hughes will helm the Over/Under pilot, which has been written by United States of Tara's Sheila Callaghan.
Fox TV studios will produce the project alongside Universal Cable Productions.
> More US Television news