The actress told Metro that the only time she worried that the series had gone too far for American audiences was when they shot a scene featuring a grandmother overdosing on cocaine.
Rossum, who plays Fiona in the show, said: "The actress who was doing it was about 93 and it was her birthday. She had clearly never used drugs because she couldn't figure out how to do it.
'She kept trying to exhale and blow out - it was extremely funny watching our director explain they would just use a hairdryer off camera and have the cocaine blown away, and that all she had to do was mime."
She joked: "It's moments like that when I thought, wow, we're all going to hell."
Her co-star William H. Macy quipped: "America is morally schizophrenic and I worried about the underage sex and the gay sex, and the gay underage sex."
> Emmy Rossum 'wears vag pad on Shameless'
> Rossum explains Shameless sex scenes
Watch our recent interview with William H. Macy below: