The police procedural airs on CBS in the US and Channel 5 in the UK, where the title is sometimes used as slang for a deranged person.
Yeoman told Metro: "Our three top executive producers are British and went into it with their eyes open but it's geared towards a US network.
"There's the initial amusement about the title - we had the definition of 'mentalism' as the tag on the show for the first two series - but I think everyone knows what it means now."
Asked about his career progress, Yeoman added: "I came out of drama school and my first audition was for the film Troy. I had the experience of being on set with legends such as Peter O'Toole and Julie Christie.
"Then I got Midsomer Murders, which is my mum's favourite show, then went back to the US and did several TV pilots and series that didn't last long."
> Malcolm McDowell confirms Mentalist return
> William Forsythe to guest in Mentalist