The Vampire Diaries actress will play a Miami bartender who is caught up in a murder investigation, according to TV Line.
When a man is found murdered at the beach, Ewell's character will become a prime suspect in the investigation led by Detective Jim Longworth (Matt Passmore).
Ewell played Vicki Donovan in the first season of The Vampire Diaries and recently returned to the show.
She also played the recurring role of Nika in the seventh season of House and has made guest appearances on CSI, Bones and Entourage.
The Glades star Matt Passmore recently claimed that "the pace is amped up a bit" in the second season, promising "a little bit more action".
The Glades continues on Sundays at 10/9c on A&E.
Watch a trailer for season two of The Glades below: