Following on from the 1991 John Grisham novel, The Firm will follow Mitch McDeere (Josh Lucas) as he emerges from the Witness Protection Programme.
Battlestar Galactica actor Rennie will play Mitch's older brother Ray McDeere.
He recently starred as Rick Felder in the first season of AMC's The Killing and has also played recurring roles on Californication and 24.
Juliette Lewis will play an unspecified role on The Firm. She received an Academy Award nomination for her role in 1991 film Cape Fear and subsequently appeared in 1994's Natural Born Killers and 1996's From Dusk Till Dawn.
The Firm will air on Sundays at 10/9c in midseason on NBC. John Grisham, Lukas Reiter, John Morayniss, Michael Rosenberg and Noreen Halpern will serve as executive producers.
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Watch John Grisham discuss NBC's The Firm below: