Eglee told the Chicago Sun-Times that the FX pilot, based on the comic series, takes elements from both the 1995 Brad Pitt thriller and the 2008 Batman film sequel.
Eglee, who serves as both an executive producer and writer on the adaptation, added that the super-powered villains in Powers will serve as "metaphors for real-life characters".
"For me it was about creating some interesting characters in a law enforcement context," he explained. "It just so happens that the bad guys [our heroes are] fighting have abilities that regular people don't have."
The Powers pilot, based on the comic series by Brian Michael Bendis, will follow homicide detectives Christian Walker and Deena Pilgrim as they investigate crimes committed by super-powered criminals.
FX president John Landgraf previously said at the Television Critics Association that Powers could reinvent the superhero genre.
"I'm not saying that Powers isn't fun, but it aspires to be a serious drama, and it's fascinating to me to try to reshape and reinvent familiar genres," he explained.
Jason Patric and Lucy Punch will play the lead roles of Walker and Pilgrim. Charles S. Dutton will appear as police department head Captain Cross in the pilot, with child actress Bailee Madison playing Walker's young ward Calista.
Canadian model and actress Carly Foulkes is believed to have been cast as celebrity superheroine Retro Girl, and Supernatural's Alona Tal will also appear in an unspecified role.