Fox, ABC and NBC are all interested in the comedian's latest project, with the latter two networks having already made offers, according to Deadline.
The single-camera comedy, co-written by Silverman and loosely based on her own life, will also be pitched to CBS in the near future.
Dan Sterling and Jon Schroeder will also contribute to the script, which follows a woman readjusting to being single after a decade spent in a relationship.
Ron Howard is said to be a major supporter of the project, having attended the pitch meetings on behalf of his production company Imagine. Silverman, Howard, Sterling, Imagine's Brian Grazer and Scoundrels veteran Francie Calfo will all serve as executive producers.
Silverman, Sterling and Schroeder previously worked together on The Sarah Silverman Program, which aired on Comedy Central from 2007 to 2010.
Since the show's conclusion, Silverman played a voice role on Fox animation Bob's Burgers and also appeared in an episode of CBS legal drama The Good Wife.
> Sarah Silverman writing new TV show?
Watch a clip from The Sarah Silverman Program below: