The Parks and Recreation actor explained that studying the clips allowed him to get more into Peterson's frame of mind and understand who he is as a person.
Lowe told Access Hollywood: "The good news is there's hours and hours of footage, so I had a library to cull through of Drew Peterson interviews and stuff shot.
"So I just immersed myself in that for weeks and weeks and weeks. I think it's gonna be interesting. It's a total departure."
Lowe added that he had "fun" taking on the role because it is completely different to his Parks and Recreation character Chris Traeger.
"It was really fun for me to do something so different, and that's what's great about this moment in my life is I'm really able to go from one extreme to the other. Drew Peterson and Chris Traeger… literally could not be more different," he said.
Lowe previously described the process of playing Peterson as "transformative".