The veteran presenter, who currently co-hosts the daytime show alongside Kelly Ripa, confirmed his departure date during Tuesday's episode.
Philbin revealed his plans to leave Live! during the January 18 episode earlier this year.
On today's episode Philbin joked: "Last January I made the announcement that I'll be moving on, but I never gave you an exact date. So I'm pushing it back five years! Just kidding!"
Philbin then laughed: '[Kelly] doesn't want to hear that! She's looking forward to some new, young, hot stud!... Don't worry the show goes on. Of course Kelly will begin trying out new co-hosts just like 11 years ago when I did the same thing and found her."
Ripa quipped: "So get your resumes in!"
Live! has yet to announce any possible replacements for Philbin, who celebrated his 80th birthday on August 25.
Watch Regis Philbin announcing his plans to leave Live! with Regis and Kelly back in January below: