Hotel Hell will see Ramsay and several hospitality experts travelling around the US to help change the fortunes of failing hotels, motels and bed & breakfasts.
Ramsay said that his own experience studying hotel management in his youth has prepared him to deal with unco-operative hotel staff and filthy rooms.
"These are stories that everyone can relate to, because virtually all of us have had a bad hotel experience that's turned a holiday or business trip into a total disaster," he said. "It's time to put the hospitality industry to the test."
Fox's president of alternative entertainment Mike Darnell said of Hotel Hell: "Gordon is amazing to work with and no matter what the premise, he delivers every time.
"With an unprecedented three shows already on the air, Gordon is an incredible television success, and we're really thrilled to put him through Hotel Hell on Fox."
Hotel Hell is produced by Ramsay's company One Potato Two Potato Inc.
An air date for Hotel Hell has not yet been announced.
On Monday night, Ramsay crowned the ninth season winner of his other Fox reality series Hell's Kitchen.
> Gordon Ramsay's Melbourne restaurants close down