The Grammy-winning singer will executive produce Mixed Blessings, according to Deadline.
The project will focus on a popular hip-hop artist who finds his single life disrupted when he discovers that he has a secret teenage son.
The potential series is loosely based on the childhood of Legend's fellow executive producer Mike Jackson.
Medium's Rob Pearlstein will also serve as writer and co-executive producer on Mixed Blessings, which attracted interest from a number of networks before landing at NBC.
The final executive producer is NBC's Teri Weinberg, while Universal Television will produce.
Other comedy projects currently in development at NBC include a sitcom from Ellen DeGeneres and Portia de Rossi, a karaoke-themed series from Maroon 5 singer and The Voice judge Adam Levine and a new show from Will & Grace star Sean Hayes.
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