Both comedies have performed strongly in the ratings for the Peacock Network in their opening episodes.
"We made comedy an important goal for us this season and I'm very pleased to be making full-season commitments to both Whitney and Up All Night," said Robert Greenblatt, chairman of NBC Entertainment.
"We're thrilled with the creative direction of both shows as well as the potential for them to continue to build loyal audiences over the coming months. We're proud of all of the producers, writers, actors and directors who have worked so hard to bring these shows to life."
Whitney is a live studio sitcom written by and starring comic Whitney Cummings. It's based around her character Whitney and her unconventional romance with Alex Green (Chris D'Elia).
Up All Night features Christina Applegate and Will Arnett as new parents Reagan and Chris, adjusting to life with a baby. It is created by Emmy winner Emily Spivey (Parks & Recreation).
> Whitney to air on Comedy Central in UK
> Whitney exec: 'People are rooting for our demise'