Fox has announced that the Matt Groening animation has been ordered for a 24th and 25th season.
The renewal follows reports that the show's future was in jeopardy due to a contract dispute between the show's voice actors and the network.
Fox had previously said in a statement: "We believe this brilliant series can and should continue, but we cannot produce future seasons under its current financial model.
"We are hopeful that we can reach an agreement with the voice cast that allows The Simpsons to go on entertaining audiences with original episodes for many years to come."
It was later claimed that several Simpsons producers had indicated a willingness to take a pay cut in order to keep the show on the air.
Fox did not reveal the terms of the new deal with the actors and producers.
The Simpsons first premiered in December 1989. It is the longest-running American sitcom, the longest-running American animated programme and the longest-running American primetime scripted television series in history.
New episodes resume on Fox at 8/7c on October 30 with 'Treehouse of Horror XXII'.
Watch executive producer Al Jean discuss The Simpsons below: